Reply: Evolutionary game theory: lessons and limitations, a cancer perspective
نویسندگان
چکیده
منابع مشابه
The ecology of cancer from an evolutionary game theory perspective.
The accumulation of somatic mutations, to which the cellular genome is permanently exposed, often leads to cancer. Analysis of any tumour shows that, besides the malignant cells, one finds other 'supporting' cells such as fibroblasts, immune cells of various types and even blood vessels. Together, these cells generate the microenvironment that enables the malignant cell population to grow and u...
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Background The physics of cancer dormancy, the time between initial cancer treatment and re-emergence after a protracted period, is a puzzle. Cancer cells interact with host cells via complex, non-linear population dynamics, which can lead to very non-intuitive but perhaps deterministic and understandable progression dynamics of cancer and dormancy. Results We explore here the dynamics of hos...
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In this paper, two games that play a role in creating a cancer tumor and suppression are studied using evolutionary game theory and its different modes are analyzed. The first game is the competition between a cancer cell and a healthy cell to receive food through the blood. In the second game, the interaction between the two oncogenes Ras and Myc is examined for cellular deformation
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The medical consultation is best understood as a two-way social interaction involving interactive decision making. Game theory—a theory based on assumptions of rational choice and focusing on interactive decision making—has the potential to provide models of the consultation that can be used to generate empirically testable predictions about the factors that promote quality of care. Three diffe...
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A new paradigm in the way we look at cancer with important implications on how we treat it is about to be published in the British Journal of Cancer by Portuguese, Belgian and American researchers. The group use a mathematical approach to reveal how by changing the dynamics of interaction between the cancer cells and those of the affected tissue – it is possible to control and even potentially ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2009
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6605445